Markus Graefen Selected Research

Hormones (Hormone)

2/2024	[Local therapies for oligometastatic hormone-sensitive prostate cancer].
10/2023	Real-world evidence of outcomes of oligometastatic hormone-sensitive prostate cancer patients treated with metastasis-directed therapy.
1/2022	Overall Survival After Systemic Treatment in High-volume Versus Low-volume Metastatic Hormone-sensitive Prostate Cancer: Systematic Review and Network Meta-analysis.
1/2022	Cytoreductive radical prostatectomy after chemohormonal therapy in patients with primary metastatic prostate cancer.
9/2021	Management and treatment options for patients with de novo and recurrent hormone-sensitive oligometastatic prostate cancer.
1/2021	Enumeration and Changes in Circulating Tumor Cells and Their Prognostic Value in Patients Undergoing Cytoreductive Radical Prostatectomy for Oligometastatic Prostate Cancer-Translational Research Results from the Prospective ProMPT trial.
1/2017	Survival Among Men at High Risk of Disseminated Prostate Cancer Receiving Initial Locally Directed Radical Treatment or Initial Androgen Deprivation Therapy.
7/2014	NY-ESO-1 expression is tightly linked to TMPRSS2-ERG fusion in prostate cancer.
8/2012	Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer.
8/2010	Analysis of testosterone suppression in men receiving histrelin, a novel GnRH agonist for the treatment of prostate cancer.

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Markus Graefen Research Topics

Disease

412	Prostatic Neoplasms (Prostate Cancer) 05/2024 - 02/2002
208	Neoplasms (Cancer) 10/2023 - 02/2002
47	Margins of Excision 12/2023 - 04/2003
42	Neoplasm Metastasis (Metastasis) 03/2024 - 11/2006
27	Carcinoma (Carcinomatosis) 05/2023 - 08/2002
24	Lymphatic Metastasis 01/2024 - 11/2003
17	Renal Cell Carcinoma (Grawitz Tumor) 01/2023 - 10/2009
15	Urinary Bladder Neoplasms (Bladder Cancer) 06/2023 - 07/2009
11	Extranodal Extension 11/2017 - 02/2004
7	Urinary Incontinence 11/2021 - 05/2011
5	Obesity 06/2022 - 08/2007
5	Erectile Dysfunction 01/2021 - 04/2007
5	7 Hereditary Prostate Cancer 07/2020 - 06/2011
4	Genomic Instability 01/2021 - 01/2020
3	Delirium 08/2022 - 03/2020
3	Kidney Neoplasms (Kidney Cancer) 06/2022 - 09/2012
3	Lymphocele 12/2021 - 02/2003
3	Disease Progression 07/2015 - 01/2009
3	Carcinogenesis 01/2015 - 09/2013
2	Pulmonary Embolism 01/2024 - 09/2015
2	Thrombosis (Thrombus) 10/2022 - 09/2015
2	Infections 01/2021 - 11/2019
2	Emergence Delirium 06/2020 - 03/2020
2	Rectal Neoplasms (Rectal Cancer) 12/2019 - 02/2010
2	Coronary Artery Disease (Coronary Atherosclerosis) 12/2014 - 09/2014
2	Inguinal Hernia (Direct Inguinal Hernia) 12/2010 - 03/2010
2	Prostatic Intraepithelial Neoplasia 11/2010 - 03/2010
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 09/2006 - 12/2003
2	Prostatic Diseases 04/2005 - 11/2002
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2024
1	Thrombophilia 01/2024
1	hereditary Thrombophilia 01/2024
1	Clear-cell metastatic renal cell carcinoma 12/2023
1	Hypertension (High Blood Pressure) 11/2023
1	Anastomotic Leak 09/2023
1	Adenocarcinoma 01/2023

Drug/Important Bio-Agent (IBA)

101	Prostate-Specific Antigen (Semenogelase)IBA 12/2023 - 03/2002
23	AndrogensIBA 01/2023 - 11/2003
23	Proteins (Proteins, Gene)FDA Link 03/2022 - 12/2005
22	AntigensIBA 05/2024 - 11/2010
20	Biomarkers (Surrogate Marker)IBA 10/2020 - 09/2005
13	Hormones (Hormone)IBA 02/2024 - 02/2004
10	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 08/2012
8	TensinsIBA 01/2020 - 08/2012
7	Androgen Receptors (Androgen Receptor)IBA 01/2023 - 03/2013
6	Docetaxel (Taxotere)FDA Link 03/2023 - 01/2022
6	DNA (Deoxyribonucleic Acid)IBA 03/2022 - 09/2006
6	Dihydrotachysterol (AT 10)IBA 10/2021 - 05/2012
5	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2023 - 01/2022
5	Serine Proteases (Serine Protease)IBA 01/2020 - 01/2013
4	enzalutamideIBA 12/2023 - 12/2020
4	AlkaloidsIBA 01/2023 - 01/2020
4	gallium 68 PSMA-11IBA 12/2021 - 03/2016
4	Protein Isoforms (Isoforms)IBA 07/2015 - 06/2004
4	Tissue Kallikreins (Tissue Kallikrein)IBA 04/2005 - 02/2003
3	Indicators and Reagents (Reagents)IBA 12/2020 - 07/2015
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2013
3	Capsules (Microcapsules)IBA 11/2016 - 06/2006
3	isopropyl cyanoacrylateIBA 01/2015 - 08/2008
3	Gonadotropin-Releasing Hormone (GnRH)FDA Link 12/2014 - 08/2010
2	A-factor (Streptomyces)IBA 01/2024 - 09/2015
2	apalutamideIBA 12/2023 - 01/2022
2	darolutamideIBA 12/2023 - 01/2022
2	Dronabinol (THC)FDA LinkGeneric 06/2023 - 09/2022
2	Guanidine (Guanidine Nitrate)FDA Link 11/2022 - 01/2020
2	taxaneIBA 11/2022 - 03/2019
2	Kallikreins (Kallikrein)IBA 01/2021 - 01/2020
2	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 07/2015
2	LigandsIBA 01/2020 - 03/2016
2	SurvivinIBA 01/2020 - 01/2020
2	6-bromo-2-naphthyl sulfate (BNS)IBA 01/2020 - 11/2012
2	Phosphotransferases (Kinase)IBA 01/2019 - 06/2008
2	Messenger RNA (mRNA)IBA 09/2017 - 02/2008
2	Testosterone (Sustanon)FDA Link 01/2017 - 08/2010
2	Histones (Histone)IBA 11/2015 - 06/2015
2	Phosphodiesterase 5 InhibitorsIBA 02/2015 - 10/2008
2	Phenobarbital (Luminal)FDA Link 01/2015 - 01/2015
2	Fluconazole (Zonal)FDA LinkGeneric 04/2007 - 07/2003
1	factor V LeidenIBA 01/2024

Therapy/Procedure

302	Prostatectomy (Retropubic Prostatectomy) 01/2024 - 02/2002
72	Therapeutics 05/2024 - 11/2003
67	Radiotherapy 03/2024 - 11/2003
49	Lymph Node Excision (Lymph Node Dissection) 12/2023 - 02/2002
22	Nephrectomy 12/2023 - 10/2009
18	Cystectomy 06/2023 - 07/2009
11	Castration 12/2023 - 01/2018
10	Drug Therapy (Chemotherapy) 03/2023 - 01/2010
8	Brachytherapy 11/2021 - 07/2007
7	Nephroureterectomy 04/2012 - 11/2009
6	Length of Stay 01/2024 - 09/2012
6	Adjuvant Radiotherapy 09/2022 - 03/2008
4	Salvage Therapy 01/2023 - 11/2003
4	Catheters 11/2021 - 07/2014
3	Aftercare (After-Treatment) 12/2023 - 01/2022
3	Treatment Delay 12/2022 - 06/2005
3	Combined Modality Therapy 01/2020 - 02/2015
3	Blood Transfusion (Blood Transfusions) 07/2014 - 04/2012
2	Neoadjuvant Therapy 02/2022 - 01/2022
2	Orchiectomy (Orchidectomy) 12/2014 - 12/2014
2	Transurethral Resection of Prostate (TURP) 05/2014 - 08/2009